Since 1994, the Cost-Effectiveness of Preventing AIDS Complications (CEPAC) team, led by Dr. Kenneth Freedberg at the Massachusetts General Hospital, has used a Monte Carlo simulation model to evaluate the cost-effectiveness of national and multinational strategies for combating HIV/AIDS. The model, first developed in response to the outbreak of the HIV/AIDS epidemic in the United States, has grown over time in both scope and application to provide comprehensive analyses for prospective treatment strategies of HIV/AIDS and AIDS-related complications, including tuberculosis and other infections.
The CEPAC team collaborates with research teams in Côte d’Ivoire, France, India, South Africa, and Zimbabwe, as well as investigators from Brigham and Women’s Hospital, the Harvard School of Public Health, Weill Cornell Medical College, and Yale University. Research from the CEPAC team has been published in several leading medical journals, including the Journal of the American Medical Association, New England Journal of Medicine, and AIDS. In December of 2008, the team won the Partners in Excellence award for Outstanding Teamwork.
Last Updated (Friday, 30 October 2009 15:03)
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Elena Losina and co-authors published an article in Clinical Infectious Diseases. This paper evaluates sex and racial/ethnic disparities in life-years lost as a result of risk behavior, late presentation, and early discontinuation of HIV care, and compares these survival losses for HIV-infected persons with losses attributable to high-risk behavior and HIV disease itself. Click here for the abstract. |
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CEPAC investigators and collaborators presented at the 47th Annual Meeting of the Infectious Diseases Society of America in Philadelphia, PA with 3 abstracts/presentations: The Survival Cost of Opt-In Consent for HIV Testing. First Author: Michael D. April Clinical Impact and Cost-Effectiveness of Treatment for Latent Tuberculosis in HIV+ Patients in India. First Author: Mai Pho Virologic Suppression on 2nd-Line Antiretroviral Therapy (ART) in a Community-Based Program in South Africa. First Author: Julie Levison (If links do not work, please click here to search for the abstracts on the conference website.) |
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Elena Losina and the CEPAC-International team published an article in PLoS Medicine. This paper projects the clinical benefits and cost-effectiveness of loss to follow-up (LTFU) prevention programs in Côte d'Ivoire (such as eliminating ART co-payments, eliminating charges to patients for opportunistic infection-related drugs, improving personnel training, and providing meals and reimbursing for transportation for participants) from a payer perspective. Click here for the abstract. |
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Welcome new RAs Jessica Becker and June Park and new biostatistician Farzad Noubary! A recent Harvard graduate, Jessica joined the CEPAC team on September 23. June Park, an MIT alum, joined the team on October 7 after finishing two years teaching on the Navaho Nation in New Mexico. Farzad Noubary is currently getting his PhD at the Harvard School of Public Health and joined the CEPAC team part-time in October to help with all of our biostatistics needs! |
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CEPAC investigators and collaborators presented at the 49th Interscience Conference on Antimicrobial Agents and Chemotherapy in San Francisco, CA with an abstract: Routine HIV Screening in France: Clinical Impact and Cost-Effectiveness. First Author: Yazdan Yazdanpanah (If link does not work, please click here to search for the abstract on the conference website.) |
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Ben Linas and co-authors published an article in JAIDS. This paper analyzes the eligibility requirements for AIDS Drug Assistance Programs in the United States that would minimize morbidity and mortality as well as contain costs. Click here for the abstract. |
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Rochelle Walensky and the CEPAC-International team published an article in Annals of Internal Medicine. This paper evaluates the optimal CD4 threshold in which to initiate antiretroviral therapy in South Africa so to inform HIV treatment decisions while the international clinical trials focusing on this issue are in progress. Click here for the abstract. |